Stem Cell Treatment To Repair Cardiac Muscle

Through advances in stem cell therapy technology, surgeons can deliver stem cells to targeted areas of the body to repair diseased or damaged tissue, including cardiac muscle damaged by a heart attack. According to StemCellDigest.net, the technique for stem cell treatment abroad both and at home involves bundling biopolymer microthreads into biological sutures and seeding the sutures with stem cells. Studies have shown that the adult bone-marrow-derived stem cells will multiply while attached to the threads and retain their ability to differentiate and grow into other cell types as regular cells normally do.

StemCellDigest.net said that with heart attack remaining the number one killer of people across a wide range of age and dispositions, patients seeking stem cell therapy abroad and at their home countries have been looking for heart treatment in particular in increasing numbers. The article continued saying that the research lab led by assistant professor of biomedical engineering at Worcester PPolytechnic Institute Glenn Gaudette mainly focused on cardiac function, exploring ways to heal damaged heart muscle and to develop cell-based methods to treat cardiac arrhythmias. Much of this work used human mesenchymal stem cells (hMSCs), which came from the bone marrow and can grow into a range of other tissues in the body, including muscle, bone, and fat. Studies by Gaudette and others showed that when hMSCs are delivered to damaged hearts, they moderately improve cardiac function. A major challenge in these stem cell treatment abroad and domestic studies, however, was getting sufficient numbers of the hMSCs to engraft into the damaged heart tissue. Prior methods of injecting the cells into the bloodstream, or directly into the heart muscle, yielded low results, with 15 percent or less of the cells injected actually surviving and attaching to the heart muscle for a successful treatment.

With most of the hMSCs delivered by injection being washed away by the bloodstream, Gaudette teamed up with George Pins, associate professor of biomedical engineering at WPI, who has developed the biopolymer microthread technology as a "scaffold" or a temporary structure to use in various applications of wound-healing and cellular therapy to address this delivery problem. The microthreads, which are about the thickness of a human hair, are made of fibrin, a protein that helps blood clot. The threads can be engineered to have different tensile strengths and to dissolve at different rates once implanted so they can be fine-tuned for a variety of applications. Conducting stem cell research Mexico and U.S. experts agree, typically involve addressing these kinds of challenges.

In this particular case, the cells taken from the microthreads began to differentiate along the pathways that lead to fat and bone tissue. "It appears that the cells we grew on the threads behave the same way we would expect mesenchymal stem cells would in vivo," Gaudette said. "So we believe these results are proof-of-principlethat we can now deliver these cells anywhere a surgeon can place a suture. That's exciting." You can view stem cell research video testimonials by patients who have been successfully treated with adult stem cell therapy. For additional information on adult stem cell research, visit www.regenerativemedicine.mx at Av. Paseo de los Hroes #10999-501 Zona Ro, Tijuana, C.P. 22010 to learn more.