Chief Minister Omar Abdullah let Manmohan know during the inauguration of the rail link that more than the economics, it was the political aspect that should form the core of fresh talks. "The basic issue of Kashmir is not about money (development), it is political in nature. The youth of Kashmir didn't pick up guns for money, but for political reasons and it is from politics that a lasting solution should be found," he said.
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The prime minister has expressed hope that the spirit in which he offered the dialogue would be reciprocated in the same spirit. But all it seems to be doing is that both separatists and unionists are using the expected dialogue to further consolidate their constituencies on the ground.
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The UCL-led research focused on patients from multiple generations of a large family who had suffered from serious recurrent fungal infections that proved lethal in some of those affected. DNA sequencing and genetic mapping techniques enabled the researchers to identify that this family had a recurrent mutation in a gene called CARD9. The team from Radboud University in the Netherlands discovered that a mutation in the gene Dectin-1 is associated with increased susceptibility to vaginal infections by fungi (primarily of the genus Candida).
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When these two genes are working correctly, Dectin-1 senses the presence of fungi and prompts the immune cells to send signals that result in CARD9 setting off a molecular response in the immune system to protect against these microorganisms. If Dectin-1 or CARD9 are mutated or missing, the immune system struggles to control Candida and may allow local or even systemic (affecting the entire body) infections to develop.
