Clinical Trial Recruitment Strategies In Oncology

Major pharmaceutical companies conduct clinical trials in many therapeutic areas, such as cardiovascular diseases, infectious diseases, oncology, metabolic disorders and central nervous system disorders.

GBI Researchs analysis finds that oncology is responsible for the most trials across the globe. The major pharmaceutical companies conducted more clinical trials in oncology than in other therapy areas during the period between 2005 and 2010.

The figure below shows the number of trials by major pharmaceutical companies such as
AstraZeneca, Bristol-Myers Squibb, Roche, Merck and Sanofi Aventis, and clearly demonstrates the prevalence of oncology trials.

Pharmaceutical companies are doing extensive research in oncology trials compared to other therapeutic areas. The higher incidence rates in cancer and increase in severity are the major drivers.

GBI Researchs analysis estimated that the cost of one trial is approximately $2.28m. As the average time of an oncology trial is 4.5 years, the average cost of a trial is $0.5m per year.

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Outsourcing of clinical trials to clinical research organizations (CROs) is becoming a major trend for pharmaceutical companies to reduce the time and cost of a trial. Outsourcing can be done for the whole trial or for part of a trial, which can be the start-up Phase, the ongoing part of the trial, or the data management part of the trial.

Outsourcing a part of the trial helps with time management and relieves the sponsor to allow them to plan better for the other important parts of the trial, which then permits those to be managed in a better way.

There are many CROs who work actively for patient recruitment. They manage their own online database of investigators, as well as the hospitals, clinics and private physicians and professionally active physicians. They have an idea about the type of patients to be obtained and about the kind and number of patients the site can provide for. Examples of CROs are D. Anderson and Company, Max Neeman, Clinlogix, PPD, and Quintiles.

GBI Research finds that pharmaceutical companies are increasingly adopting e-clinical trial solutions in the drug development phase. The economic downturn, increased competition, patent expiry and the drying up of pipelines are pressurizing the biopharmaceutical industry to adopt eclinical trial solutions and services that could optimize the drug development process and cut down costs.

GBI Research, the leading business intelligence provider, has released its latest research,
Clinical Trial Recruitment Strategies in Oncology - Online Recruitment Methods and Use of IT-enabled Patient Management Systems Will Reduce Recruitment Time and Cost, which provides insights into recruitment strategies, challenges and solutions for on-time recruitment in oncology trials. The report also examines case studies to illustrate enhanced recruitment in a shorter time. The report provides an in-depth analysis of the trials conducted by major pharmaceutical companies for the top five oncology therapeutic indications, which are breast cancer, colorectal cancer, prostate cancer, lung cancer and brain cancer.

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