An African Mango Extract derived from a West African fruit could possibly aid overweight folks shed pounds and lower their cholesterol, a new study suggests.
The extract comes from Irvingia gabonensis, also known as African mango, a fruit generally eaten in West Africa. Lab study has shown that extracts from the plant's seed could possibly inhibit body fat production, through effects on certain genes and enzymes that regulate metabolism.
For the current study, researchers at the University of Yaounde in Cameroon randomly assigned 102 overweight adults to take either the plant extract or a placebo twice a day for 10 weeks. The study participants did not follow any special diet and were told to maintain their regular physical exercise levels.
By the end of the study, the extract group had lost a considerable amount of weight - an average of roughly 12.five kilograms - although the placebo group showed just about no change.
At the identical time, they showed declines in "bad" LDL cholesterol and blood sugar levels.
Dr. Julius E. Oben and his colleagues report the findings in the on the internet journal Lipids in Well being and Illness. The Fairfield, California-based Gateway Well being Alliances, Inc. supplied the Irvingia gabonensis extract and partially funded the study.
The study will be the very first well-controlled clinical trial of the extract's effectiveness as a weight-loss aid, the researchers note. But the findings, they write, suggest that Irvingia gabonensis could present a "useful tool" for battling the growing worldwide challenge of obesity and its related ills.
Several patients on the extract reported side effects, such as headaches, sleep difficulties and gas, but the rates were comparable in the placebo group.
The findings, Oben's team concludes, must "provide impetus for much larger clinical studies."The
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